REVERSING PKD Logo

HEALING Polycystic kidney disease one bite at a time.

References for “Reversing Polycystic Kidney Disease”

Reference List for Reversing Polycystic Kidney Disease Get the Written Copy Here

Introduction

  1. Torres JA, Kruger SL, Broderick C, Amarlkhagva T, Agrawal S, Dodam JR, Mrug M, Lyons LA, Weimbs T. Ketosis Ameliorates Renal Cyst Growth in Polycystic Kidney Disease. Cell Metab 2019; 30(6): 1007-1023.e5. doi: 10.1016/j.cmet.2019.09.012. PMID: 31631001; PMCID: PMC6904245.

Chapter 1: What is PKD?

  1. Li SR, Gulieva RE, Helms L, Cruz NM, Vincent T, Fu H, Himmelfarb J, Freedman BS. Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease. Nat Commun 2022; 13(1): 7918. doi: 10.1038/s41467-022-35537-2. PMID: 36564419.

Chapter 2: Basic molecular mechanisms of PKD

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  2. Zhang Z, et al. Detection of PKD1 and PKD2 Somatic Variants in Autosomal Dominant Polycystic Kidney Cyst Epithelial Cells by Whole-Genome Sequencing. J Am Soc Nephrol 2021; 32(12): 3114-3129.
  3. Dethlefsen MM, Bertholdt L, Gudiksen A, Stankiewicz T, Bangsbo J, van Hall G, Plomgaard P, Pilegaard H. Training state and skeletal muscle autophagy in response to 36 h of fasting. J Appl Physiol 2018; 125(5): 1609-1619. doi: 10.1152/japplphysiol.01146.2017. PMID: 30161009.
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Chapter 3: Looking deeper – The X factor

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  9. Trott JF, Hwang VJ, Ishimaru T, et al. Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis. Am J Physiol Renal Physiol 2018; 315(6): F1855-F1868. doi: 10.1152/ajprenal.00025.2018.
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Chapter 4: The template for the PKDproof program

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  4. Menezes LF, Lin CC, Zhou F, Germino GG. Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease. EBioMedicine 2016; 5: 183-192. doi: 10.1016/j.ebiom.2016.01.027. PMID: 27077126; PMCID: PMC4816756.
  5. Jin R, Hao J, Yi Y, Yin D, et al. Dietary Fats High in Linoleic Acids Impair Antitumor T-cell Responses by Inducing E-FABP-Mediated Mitochondrial Dysfunction. Cancer Res 2021; 81(20): 5296-5310. doi: 10.1158/0008-5472.CAN-21-0757. PMID: 34400394; PMCID: PMC8530923.
  6. Cassina L, Chiaravalli M, Boletta A. Increased mitochondrial fragmentation in polycystic kidney disease acts as a modifier of disease progression. FASEB J 2020; 34(5): 6493-6507. doi: 10.1096/fj.201901739RR. Epub 2020 Apr 2. PMID: 32239723.
  7. Senyilmaz-Tiebe D, Pfaff DH, Virtue S, Schwarz KV, et al. Dietary stearic acid regulates mitochondria in vivo in humans. Nat Commun 2018; 9(1): 3129. doi: 10.1038/s41467-018-05614-6. PMID: 30087348.
  8. Plourde M, Cunnane SC. Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements. Appl Physiol Nutr Metab 2007; 32(4): 619-634. doi: 10.1139/H07-034. Erratum in: Appl Physiol Nutr Metab 2008; 33(1): 228-229. PMID: 17622276.

Chapter 5: How to do the PKDproof program right

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  3. Satirapoj B, Vongwattana P, Supasyndh O. Very low protein diet plus ketoacid analogs of essential amino acids supplement to retard chronic kidney disease progression. Kidney Res Clin Pract 2018; 37(4): 384-392. doi: 10.23876/j.krcp.18.0055.
  4. Hahn D, Hodson EM, Fouque D. Low protein diets for non-diabetic adults with chronic kidney disease. Cochrane Database Syst Rev 2020; 10(10): CD001892. doi: 10.1002/14651858.CD001892.pub5. PMID: 33118160.
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Chapter 6: Adjustments for low kidney function

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Chapter 7: Weekly schedule – timing

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  2. Zhao C, Cao Y, Zhang Z, Nie D, Li Y. Cinnamon and Eucalyptus Oils Suppress the Inflammation Induced by Lipopolysaccharide In Vivo. Molecules 2021; 26(23): 7410. doi: 10.3390/molecules26237410. PMID: 34885991; PMCID: PMC8659246.
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Chapter 8: Common myths

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  3. Roddy E, Choi HK. Epidemiology of gout. Rheum Dis Clin North Am 2014; 40(2): 155-175. doi: 10.1016/j.rdc.2014.01.001. PMID: 24703341; PMCID: PMC4119792.
  4. Lee JE, McLerran DF, Rolland B, Chen Y, et al. Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies. Am J Clin Nutr 2013; 98(4): 1032-1041. doi: 10.3945/ajcn.113.062638. PMID: 23902788; PMCID: PMC3778858.

Chapter 9: Lifestyle strategies

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Chapter 10: Tracking your progress

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Chapter 11: What to do regularly

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  14. Reizine F, Grégoire M, Lesouhaitier M, Coirier V, et al. Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction. Proceedings of the National Academy of Sciences of the United States of America 2022; 119. doi: 10.1073/pnas.2115139119.
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  18. McFarlin BK, Henning AL, Bowman EM, Gary MA, Carbajal KM. Oral spore-based probiotic supplementation was associated with reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers. World J Gastrointest Pathophysiol 2017; 8(3): 117-126. doi: 10.4291/wjgp.v8.i3.117. PMID: 28868181; PMCID: PMC5561432.

Chapter 12: Common pitfalls

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  2. Howard M, Howard G, Orrego D. Resolving Pulmonary Artery Intimal Sarcoma via the Standard of Care combined with Metabolic Therapies. Version 3.5: 27 August 2023. Retrieved from https://www.youtube.com/watch?v=pm2ia_Nsfc8 11 May 2024.

Chapter 13: About common medications

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  6. Yamal J, Martinez J, Osani MC, Du XL, et al. Mortality and Morbidity Among Individuals with Hypertension Receiving a Diuretic, ACE Inhibitor, or Calcium Channel Blocker: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open 2023; 6(12): e2344998. doi: 10.1001/jamanetworkopen.2023.44998.
  7. Zhou X, Davenport E, Ouyang J, Hoke ME, et al. Pooled Data Analysis of the Long-Term Treatment Effects of Tolvaptan in ADPKD. Kidney Int Rep 2022; 7(5): 1037-1048. doi: 10.1016/j.ekir.2022.02.009. PMID: 35570988; PMCID: PMC9091612.
  8. U.S. Food and Drug Administration. (2013, April 30). FDA Drug Safety Communication: FDA limits duration and usage of Samsca (tolvaptan) due to possible liver injury leading to organ transplant or death. www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-limits-duration-and-usage-samsca-tolvaptan-due-possible-liver.
  9. Perneger TV, Whelton PK, Klag MJ. Risk of kidney failure associated with the use of acetaminophen, aspirin, and nonsteroidal antiinflammatory drugs. N Engl J Med 1994; 331(25): 1675-1679. doi: 10.1056/NEJM199412223312502. PMID: 7969358.
  10. Loomans-Kropp HA, Pinsky P, Cao Y, Chan AT, Umar A. Association of Aspirin Use With Mortality Risk Among Older Adult Participants in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. JAMA Netw Open 2019; 2(12): e1916729. doi: 10.1001/jamanetworkopen.2019.16729. Erratum in: JAMA Netw Open 2020; 3(1): e1921081. PMID: 31800071; PMCID: PMC6902761.
  11. Park A. Should You Take a Daily Aspirin to Prevent Heart Attacks or Strokes? Time 1 December 2016. https://time.com/4586868/daily-aspirin-heart-attacks/ (Accessed 20 Feb 2024).

Chapter 14: Barriers to healing

  1. Ross E. The Paleo Thyroid Solution 2nd Edition. Bradventures LLC; 2020.
  2. Kalish D. The Kalish Method: Healing the Body, Mapping the Mind. (Please add publication year here).
  3. Brandão R, Santos FW, Zeni G, Rocha JB, Nogueira CW. DMPS and N-acetylcysteine induced renal toxicity in mice exposed to mercury. Biometals 2006; 19(4): 389-398. doi: 10.1007/s10534-005-4020-3. PMID: 16841248.
  4. Zalups RK, Gelein RM, Cernichiari E. DMPS as a rescue agent for the nephropathy induced by mercuric chloride. J Pharmacol Exp Ther 1991; 256(1): 1-10. PMID: 1671092.
  5. Nathan N. Toxic: Heal Your Body from Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and Chronic Environmental Illness. Victory Belt; 2018.
  6. Levy TE. Hidden Epidemic: Silent Oral Infections Cause Most Heart Attacks and Breast Cancers. Medfox Publishing; 2017.

Appendices: III FAQs

  1. Hattah DKA, Sjahril R, Sriwijaya S. The Turbidity, pH, Direct Gram as Predictors of Symptomatic Urinary Tract Infections in Pregnant Women. Nusantara Medical Science Journal 2022; 7(2): 98-105.

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