Li SR, Gulieva RE, Helms L, Cruz NM, Vincent T, Fu H, Himmelfarb J,
Freedman BS. Glucose absorption drives
cystogenesis in a human organoid-on-chip model of polycystic kidney
disease.Nat Commun 2022;
13(1): 7918. doi:
10.1038/s41467-022-35537-2. PMID: 36564419.
Chapter 2: Basic molecular mechanisms of PKD
Lanktree MB, Haghighi A, Guiard E, et al. Prevalence
Estimates of Polycystic Kidney and Liver Disease by Population
Sequencing.J Am Soc Nephrol
2018; 29(10): 2593-2600. doi:
10.1681/ASN.2018050493. PMID: 30135240;
PMCID: PMC6171271.
Zhang Z, et al. Detection of PKD1 and
PKD2 Somatic Variants in Autosomal Dominant Polycystic Kidney Cyst
Epithelial Cells by Whole-Genome Sequencing.J
Am Soc Nephrol 2021; 32(12): 3114-3129.
Dethlefsen MM, Bertholdt L, Gudiksen A, Stankiewicz T, Bangsbo J, van
Hall G, Plomgaard P, Pilegaard H. Training
state and skeletal muscle autophagy in response to 36 h of fasting.J Appl Physiol 2018; 125(5):
1609-1619. doi:
10.1152/japplphysiol.01146.2017. PMID: 30161009.
Homer B. VO2 Max Essentials Part IV:
Field tests for estimating VO2 max.www.physiologicallyspeaking.com
7 June 2023. Accessed 19 Feb 2024.
Bellamy E. Exogenous ketones
comparison (Ketone esters, ketone salts and C8 MCT oil) – experiment
results.Ketosource 24
January 2019. Accessed
19 Feb 2024.
Chapter 3: Looking deeper – The X factor
Offer DEMY, Woodhouse MA. Toxic
metabolic defect in polycystic disease of kidney. Evidence from
microscope studies.Lancet
1970; 1(7646): 547-50.
Yamaguchi T, et al. Cyst fluid from a
murine model of polycystic kidney disease stimulates fluid secretion,
cyclic adenosine monophosphate accumulation, and cell proliferation by
Madin-Darby canine kidney cells in vitro.Am
J Kidney Dis 1995; 25(3): 471-477.
Grantham JJ, et al. Evidence for a
potent lipid secretagogue in the cyst fluids of patients with
autosomal dominant polycystic kidney disease.J
Am Soc Nephrol 1995; 6(4): 1242-1249.
Avner ED, et al. Regression of
genetically determined polycystic kidney disease in murine organ
culture.Experientia 1986;
42(1): 77-80.
Miller-Hjelle MA, et al. Polycystic
kidney disease: an unrecognized emerging infectious disease?Emerg Infect Dis 1997; 3(2): 113-127.
Gardner KD, Reed WP, Evan AP, et al. Endotoxin
provocation of experimental renal cystic disease.Kidney
Int 1987; 32(3): 329-334. doi:
10.1038/ki.1987.213.
Miller MA, Prior RB, Horvath FJ, Hjelle JT. Detection
of endotoxiuria in polycystic kidney disease patients by the use of
the Limulus amebocyte lysate assay.Am
J Kidney Disease 1990; 15(2): 117-122. doi:
10.1016/s0272-6386(12)80508-7.
Tremellen K, Pearce K. Dysbiosis of
Gut Microbiota (DOGMA)-a novel theory for the development of
Polycystic Ovarian Syndrome.Med
Hypotheses 2012; 79(1): 104-112.
Trott JF, Hwang VJ, Ishimaru T, et al. Arginine
reprogramming in ADPKD results in arginine-dependent cystogenesis.Am J Physiol Renal Physiol 2018;
315(6): F1855-F1868. doi:
10.1152/ajprenal.00025.2018.
Gardner KD, Jr, Evan AP, Reed WP. Accelerated
renal cyst development in deconditioned germ-free rats.Kidney Int 1986; 29(6): 1116-1123.
Nolan JP. The role of intestinal
endotoxin in liver injury: a long and evolving history.Hepatology 2010; 52(5): 1829-1835.
Meghji S, Qureshi W, Henderson B, Harris M. The
role of endotoxin and cytokines in the pathogenesis of odontogenic
cysts.Arch Oral Biol 1996;
41(6): 523-531. doi:
10.1016/0003-9969(96)00032-5.
Neudorf H, Durrer C, Myette-Cote E, et al. Oral
Ketone Supplementation Acutely Increases Markers of NLRP3 Inflammasome
Activation in Human Monocytes.Mol
Nutr Food Res 2019; 63(11): e1801171. doi:
10.1002/mnfr.201801171.
Chapter 4: The template for the PKDproof program
Stallings VA, Adgent MA, Umbach DA, Zemel BS, et al. Soy-Based
Infant Formula Feeding and Impact on Estrogen-Responsive Tissue.FASEB Journal 2017; 31: 958.2-958.2. doi:
10.1096/fasebj.31.1_supplement.958.2.
Berndt WO, Hayes AW, Phillips RD. Effects
of mycotoxins on renal function: mycotoxic nephropathy.Kidney Int 1980; 18(5): 656-664. doi:
10.1038/ki.1980.183. PMID: 7463958.
Sauer LA, Blask DE, Dauchy RT. Dietary
factors and growth and metabolism in experimental tumors.J Nutr Biochem 2007; 18(10): 637-649. doi:
10.1016/j.jnutbio.2006.12.009. PMID: 17418560.
Menezes LF, Lin CC, Zhou F, Germino GG. Fatty
Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal
Dominant Polycystic Kidney Disease.EBioMedicine
2016; 5: 183-192. doi:
10.1016/j.ebiom.2016.01.027. PMID: 27077126;
PMCID: PMC4816756.
Jin R, Hao J, Yi Y, Yin D, et al. Dietary
Fats High in Linoleic Acids Impair Antitumor T-cell Responses by
Inducing E-FABP-Mediated Mitochondrial Dysfunction.Cancer
Res 2021; 81(20): 5296-5310. doi:
10.1158/0008-5472.CAN-21-0757. PMID: 34400394;
PMCID: PMC8530923.
Cassina L, Chiaravalli M, Boletta A. Increased
mitochondrial fragmentation in polycystic kidney disease acts as a
modifier of disease progression.FASEB
J 2020; 34(5): 6493-6507. doi:
10.1096/fj.201901739RR. Epub 2020 Apr 2. PMID: 32239723.
Senyilmaz-Tiebe D, Pfaff DH, Virtue S, Schwarz KV, et al. Dietary
stearic acid regulates mitochondria in vivo in humans.Nat
Commun 2018; 9(1): 3129. doi:
10.1038/s41467-018-05614-6. PMID: 30087348.
Plourde M, Cunnane SC. Extremely
limited synthesis of long chain polyunsaturates in adults:
implications for their dietary essentiality and use as supplements.Appl Physiol Nutr Metab 2007; 32(4):
619-634. doi: 10.1139/H07-034.
Erratum in: Appl Physiol Nutr Metab 2008; 33(1): 228-229. PMID: 17622276.
Chapter 5: How to do the PKDproof program right
Pollack. The Fourth Phase of Water:
Beyond solid, liquid and vapor. Ebner & Sons; 2013.
Howard M, Howard G, Orrego D. Resolving
Pulmonary Artery Intimal Sarcoma via the Standard of Care combined
with Metabolic Therapies. Version 3.5: 27 August 2023.
Retrieved from https://www.youtube.com/watch?v=pm2ia_Nsfc8
11 May 2024.
Satirapoj B, Vongwattana P, Supasyndh O. Very
low protein diet plus ketoacid analogs of essential amino acids
supplement to retard chronic kidney disease progression.Kidney Res Clin Pract 2018; 37(4):
384-392. doi:
10.23876/j.krcp.18.0055.
Hahn D, Hodson EM, Fouque D. Low
protein diets for non-diabetic adults with chronic kidney disease.Cochrane Database Syst Rev 2020;
10(10): CD001892. doi:
10.1002/14651858.CD001892.pub5. PMID: 33118160.
Obeid W, Hiremath S, Topf JM. Protein
Restriction for CKD: Time to Move On.Kidney360
2022; 3(9): 1611-1615. doi:
10.34067/KID.0001002022. PMID: 36245656.
Zamami R, Kohagura K, Kinjyo K, et al. The
Association between Glomerular Diameter and Secondary Focal Segmental
Glomerulosclerosis in Chronic Kidney Disease.Kidney
Blood Press Res 2021; 46(4): 433-440. doi:
10.1159/000515528. PMID: 34315152.
Kontessis P, Jones S, Dodds R, et al. Renal,
metabolic and hormonal responses to ingestion of animal and vegetable
proteins.Kidney Int 1990;
38(1): 136-144. doi:
10.1038/ki.1990.178.
Phillips SM, Van Loon LJ. Dietary
protein for athletes: from requirements to optimum adaptation.J Sports Sci 2011; 29 Suppl 1:
S29-S38. doi:
10.1080/02640414.2011.619204. PMID: 22150425.
Bellarby J, Tirado R, Leip A, Weiss F, Lesschen JP, Smith P. Livestock
greenhouse gas emissions and mitigation potential in Europe.Glob Chang Biol 2013; 19(1): 3-18. doi:
10.1111/j.1365-2486.2012.02786.x. PMID: 23504717.
Salatin J. TEDx Talks: Cows, Carbon
and Climate. TEDxCharlottesville [Video]. YouTube 14 January
2016. www.youtube.com/watch?v=exampleURL.
Liu CM, Stegger M, Aziz M, et al. Escherichia
coli ST131-H22 as a Foodborne Uropathogen.mBio
2018; 9(4): e00470-18. doi:
10.1128/mBio.00470-18. PMID: 30154256.
EWG (Environmental Working Group). (2003).
PCBs in Farmed Salmon. Environmental Working Group 312 July
2003. www.ewg.org/research/pcbs-farmed-salmon.
(Accessed 20 Feb 2024).
Mazi TA, Stanhope KL. Elevated
Erythritol: A Marker of Metabolic Dysregulation or Contributor to the
Pathogenesis of Cardiometabolic Disease?Nutrients
2023; 15(18): 4011. doi:
10.3390/nu15184011. PMID: 37764794.
Torres VE, Chapman AB, Devuyst O, Gansevoort RT, et al. TEMPO
3:4 Trial Investigators. Tolvaptan in patients with autosomal dominant
polycystic kidney disease.N Engl J
Med 2012; 367(25): 2407-2418. doi:
10.1056/NEJMoa1205511. PMID: 23121377;
PMCID: PMC3760207.
Rangan GK, Wong ATY, Munt A, et al. Prescribed
Water Intake in Autosomal Dominant Polycystic Kidney Disease.NEJM Evidence 2022; 1(1): EVIDoa2100021. doi:
10.1056/EVIDoa2100021.
Dev H, Zhu C, Barash I, Blumenfeld JD, et al. Feasibility
of Water Therapy for Slowing Autosomal Dominant Polycystic Kidney
Disease Progression.Kidney360
2024 Apr 1. doi:
10.34067/KID.0000000000000428. Epub ahead of print. PMID: 38556640.
Chapter 6: Adjustments for low kidney function
Jing S-B, Li L, Ji D, et al. Effect of
Chitosan on Renal Function in Patients with Chronic Renal Failure.Journal of Pharmacy and Pharmacology
1997; 49(7): 721–723. doi:
10.1111/j.2042-7158.1997.tb06099.x.
Hassan W, Shrestha P, Sumida K, et al. Association
of Uric Acid–Lowering Therapy With Incident Chronic Kidney Disease.JAMA Netw Open 2022; 5(6): e2215878. doi:
10.1001/jamanetworkopen.2022.15878.
Yang Y, Zhou Y, Cheng S, Sun JL, Yao H, Ma L. Effect
of uric acid on mitochondrial function and oxidative stress in
hepatocytes.Genet Mol Res
2016; 15(2). doi:
10.4238/gmr.15028644. PMID: 27420973.
Qi X, Guan K, Liu C, Chen H, Ma Y, Wang R. Whey
protein peptides PEW and LLW synergistically ameliorate hyperuricemia
and modulate gut microbiota in potassium oxonate and
hypoxanthine-induced hyperuricemic rats.J
Dairy Sci 2023; 106(11): 7367-7381. doi:
10.3168/jds.2023-23369. PMID: 37562644.
Pingali U, et al. A randomized,
double-blind, positive-controlled, prospective, dose-response clinical
study to evaluate the efficacy and tolerability of an aqueous extract
of Terminalia bellerica in lowering uric acid and creatinine levels in
chronic kidney disease subjects with hyperuricemia.BMC
Complement Med Ther 2020; 20(1): 281.
Jelkmann W, et al. Effects of
antioxidant vitamins on renal and hepatic erythropoietin production.Kidney Int 1997; 51(2): 497-501.
Wagner GS, Tephly TR. A possible role
of copper in the regulation of heme biosynthesis through
ferrochelatase.Adv Exp Med Biol
1975; 58(00): 343-354.
Chapter 7: Weekly schedule – timing
Jo H, Cha B, Kim H, Brito S, Kwak BM, Kim ST, Bin BH, Lee MG. α-Pinene Enhances the Anticancer Activity of
Natural Killer Cells via ERK/AKT Pathway.Int
J Mol Sci 2021; 22(2): 656. doi:
10.3390/ijms22020656. PMID: 33440866;
PMCID: PMC7826552.
Zhao C, Cao Y, Zhang Z, Nie D, Li Y. Cinnamon
and Eucalyptus Oils Suppress the Inflammation Induced by
Lipopolysaccharide In Vivo.Molecules
2021; 26(23): 7410. doi:
10.3390/molecules26237410. PMID: 34885991;
PMCID: PMC8659246.
Li Y, Fu X, Ma X, Geng S, et al. Intestinal
Microbiome-Metabolome Responses to Essential Oils in Piglets.Front Microbiol 2018; 9: 1988. doi:
10.3389/fmicb.2018.01988. PMID: 30210470;
PMCID: PMC6120982.
Davis SL. The least harm principle may
require that humans consume a diet containing large herbivores, not a
vegan diet.Journal of Agricultural
and Environmental Ethics 2003; 16(4): 387-394. https://philpapers.org/rec/DAVTLH.
Srikanthan P, Karlamangla AS. Muscle
mass index as a predictor of longevity in older adults.Am J Med 2014; 127(6): 547-553. doi:
10.1016/j.amjmed.2014.02.007. PMID: 24561114.
Lucas PA, Meadows JH, Roberts DE, Coles GA. The
risks and benefits of a low protein-essential amino acid-keto acid
diet.Kidney Int 1986;
29(5): 995-1003. doi:
10.1038/ki.1986.99. PMID: 3723930.
Houser J, Komarek J, Kostlanova N, Cioci G, et al. A
Soluble Fucose-Specific Lectin from Aspergillus fumigatus Conidia –
Structure, Specificity and Possible Role in Fungal Pathogenicity.PLOS ONE 2013; 8(12): e83077. doi:
10.1371/journal.pone.0083077.
Chapter 8: Common myths
Girardat-Rotar L, Puhan MA, Braun J, Serra AL. Long-term
effect of coffee consumption on autosomal dominant polycystic kidneys
disease progression: results from the Suisse ADPKD, a Prospective
Longitudinal Cohort Study.J
Nephrol 2018; 31(1): 87-94. doi:
10.1007/s40620-017-0396-8. PMID: 28386880;
PMCID: PMC5778163.
Martins ML, Martins HM, Gimeno A. Incidence
of microflora and of ochratoxin A in green coffee beans (Coffea
arabica).Food Addit Contam
2003; 20(12): 1127-1131. doi:
10.1080/02652030310001620405. PMID: 14726276.
Lee JE, McLerran DF, Rolland B, Chen Y, et al. Meat
intake and cause-specific mortality: a pooled analysis of Asian
prospective cohort studies.Am J
Clin Nutr 2013; 98(4): 1032-1041. doi:
10.3945/ajcn.113.062638. PMID: 23902788;
PMCID: PMC3778858.
Pchelin P, Shkarupa D, Smetanina N, Grigorieva T, Lapshin R,
Schelchkova N, Machneva T, Bavrina A. Red
light photobiomodulation rescues murine brain mitochondrial
respiration after acute hypobaric hypoxia.J
Photochem Photobiol B 2023; 239: 112643. doi:
10.1016/j.jphotobiol.2022.112643. PMID: 36610350.
Austin E, Huang A, Wang JY, Cohen M, Heilman E, Maverakis E, Michl J,
Jagdeo J. Red Light Phototherapy Using
Light-Emitting Diodes Inhibits Melanoma Proliferation and Alters Tumor
Microenvironments.Front Oncol
2022; 12: 928484. doi:
10.3389/fonc.2022.928484. PMID: 35847848;
PMCID: PMC9278815.
Millet-Boureima C, Rozencwaig R, Polyak F, Gamberi C. Cyst
Reduction by Melatonin in a Novel Drosophila Model of Polycystic
Kidney Disease.Molecules
2020; 25(22): 5477. doi:
10.3390/molecules25225477. PMID: 33238462;
PMCID: PMC7700119.
Arangino S, Cagnacci A, Angiolucci M, Vacca AM, Longu G, Volpe A,
Melis GB. Effects of melatonin on
vascular reactivity, catecholamine levels, and blood pressure in
healthy men.Am J Cardiol
1999; 83(9): 1417-1419. doi:
10.1016/s0002-9149(99)00112-5. PMID: 10235107.
Chapter 10: Tracking your progress
Strubl S, et al. Ketogenic dietary
interventions in autosomal dominant polycystic kidney disease-a
retrospective case series study: first insights into feasibility,
safety and effects.Clin Kidney J
2022; 15(6): 1079-1092. doi:
10.1093/ckj/sfab070.
Borsche L, Glauner B, von Mendel J. COVID-19
Mortality Risk Correlates Inversely with Vitamin D3 Status, and a
Mortality Rate Close to Zero Could Theoretically Be Achieved at 50
ng/mL 25(OH)D3: Results of a Systematic Review and Meta-Analysis.Nutrients 2021; 13(10): 3596. doi:
10.3390/nu13103596. PMID: 34684596.
Marshall RP, Droste JN, Giessing J, Kreider RB. Role
of Creatine Supplementation in Conditions Involving Mitochondrial
Dysfunction: A Narrative Review.Nutrients
2022; 14(3): 529. doi:
10.3390/nu14030529. PMID: 35276888.
Mercola J. Ketofast: Rejuvenate your
health with a step-by-step guide to timing your ketogenic meals.
Hay House; 2021.
Mercola J. The Ketofast Cookbook:
Recipes for intermittent fasting and timed ketogenic meals. Hay
House; 2019.
Vendramini LC, Nishiura JL, Baxmann AC, Heilberg IP. Caffeine
intake by patients with autosomal dominant polycystic kidney disease.Braz J Med Biol Res 2012; 45(9):
834-840. doi:
10.1590/s0100-879×2012007500120. PMID: 22801417.
Ito S. High-intensity interval
training for health benefits and care of cardiac diseases – The key to
an efficient exercise protocol.World
J Cardiol 2019; 11(7): 171-188. doi:
10.4330/wjc.v11.i7.171. PMID: 31565193.
Francois ME, Little JP. Effectiveness
and safety of high-intensity interval training in patients with type 2
diabetes.Diabetes Spectr
2015; 28(1): 39-44. doi:
10.2337/diaspect.28.1.39. PMID: 25717277.
Creighton Personal Training. HIRT – A
Safer, More Effective Alternative to HIIT.www.creightonpt.com.
Agostini D, Natalucci V, Baldelli G, De Santi M, et al. New
Insights into the Role of Exercise in Inhibiting mTOR Signaling in
Triple-Negative Breast Cancer.Oxid
Med Cell Longev 2018; 2018: 5896786. doi:
10.1155/2018/5896786. PMID: 30363988;
PMCID: PMC6186337.
Zhu Y, Teng T, Wang H, Guo H, et al. Quercetin
inhibits renal cyst growth in vitro and via parenteral injection in a
polycystic kidney disease mouse model.Food
Funct 2018; 9(1): 389-396. doi:
10.1039/c7fo01253e. PMID: 29215110.
Vicente-Vicente L, González-Calle D, Casanova AG, Hernández-Sánchez
MT, et al. Promising Clinical Candidate
for the Prevention of Contrast-Induced Nephropathy.Int
J Mol Sci 2019; 20(19): 4961. doi:
10.3390/ijms20194961. PMID: 31597315.
Clifton PM. Effect of Grape Seed
Extract and Quercetin on Cardiovascular and Endothelial Parameters in
High-Risk Subjects.J Biomed
Biotechnol 2004; 2004(5): 272-278. doi:
10.1155/S1110724304403088. PMID: 15577189.
Lu NT, Crespi CM, Liu NM, Vu JQ, et al. A
Phase I Dose Escalation Study Demonstrates Quercetin Safety and
Explores Potential for Bioflavonoid Antivirals in Patients with
Chronic Hepatitis C.Phytother Res
2016; 30(1): 160-1688. doi:
10.1002/ptr.5518. Epub 2015 Dec 1. PMID: 26621580;
PMCID: PMC5590840.
Stettner N, Rosen C, Bernshtein B, Gur-Cohen S, et al. Induction
of Nitric-Oxide Metabolism in Enterocytes Alleviates Colitis and
Inflammation-Associated Colon Cancer.Cell
Rep 2018; 23(7): 1962-1976. doi:
10.1016/j.celrep.2018.04.053. PMID: 29768197;
PMCID: PMC5976577.
Reizine F, Grégoire M, Lesouhaitier M, Coirier V, et al. Beneficial
effects of citrulline enteral administration on sepsis-induced T cell
mitochondrial dysfunction.Proceedings
of the National Academy of Sciences of the United States of America
2022; 119. doi:
10.1073/pnas.2115139119.
Suzuki T, Morita M, Kobayashi Y, Kamimura A. Oral
L-citrulline supplementation enhances cycling time trial performance
in healthy trained men: Double-blind randomized placebo-controlled
2-way crossover study.J Int Soc
Sports Nutr 2016; 13: 6. doi:
10.1186/s12970-016-0117-z. PMID: 26900386;
PMCID: PMC4759860.
Papadia C, Osowska S, Cynober L, Forbes A. Citrulline
in health and disease. Review on human studies.Clin
Nutr 2018; 37(6 Pt A): 1823-1828. doi:
10.1016/j.clnu.2017.10.009. PMID: 29107336.
Romero MJ, Yao L, Sridhar S, Bhatta A, Dou H, Ramesh G, Brands MW,
Pollock DM, Caldwell RB, Cederbaum SD, Head CA, Bagi Z, Lucas R,
Caldwell RW. l-Citrulline Protects from
Kidney Damage in Type 1 Diabetic Mice.Front
Immunol 2013; 4: 480. doi:
10.3389/fimmu.2013.00480. PMID: 24400007;
PMCID: PMC3871963.
McFarlin BK, Henning AL, Bowman EM, Gary MA, Carbajal KM. Oral
spore-based probiotic supplementation was associated with reduced
incidence of post-prandial dietary endotoxin, triglycerides, and
disease risk biomarkers.World J
Gastrointest Pathophysiol 2017; 8(3): 117-126. doi:
10.4291/wjgp.v8.i3.117. PMID: 28868181;
PMCID: PMC5561432.
Chapter 12: Common pitfalls
Kephart WC, Mumford PW, Mao X, Romero MA, et al. The
1-Week and 8-Month Effects of a Ketogenic Diet or Ketone Salt
Supplementation on Multi-Organ Markers of Oxidative Stress and
Mitochondrial Function in Rats.Nutrients
2017; 9(9): 1019. doi:
10.3390/nu9091019. PMID: 28914762.
Howard M, Howard G, Orrego D. Resolving
Pulmonary Artery Intimal Sarcoma via the Standard of Care combined
with Metabolic Therapies. Version 3.5: 27 August 2023.
Retrieved from https://www.youtube.com/watch?v=pm2ia_Nsfc8
11 May 2024.
Chapter 13: About common medications
Nagao S, Nishii K, Yoshihara D, et al. Calcium
channel inhibition accelerates polycystic kidney disease progression
in the Cy/+ rat.Kidney Int
2008; 73(3): 269-277. doi:
10.1038/sj.ki.5002629. PMID: 17943077.
Haider DG, Sauter T, Lindner G, Masghati S, et al. Use
of calcium channel blockers is associated with mortality in patients
with chronic kidney disease.Kidney
and Blood Pressure Research 2015; 40(6): 630-638. doi:
10.1159/000368539.
Stoschitzky K, Sakotnik A, Lercher P, Zweiker R, Maier R, Liebmann P,
Lindner W. Influence of beta-blockers on
melatonin release.Eur J Clin
Pharmacol 1999; 55(2): 111-115. doi:
10.1007/s002280050604. PMID: 10335905.
Scheer FA, Morris CJ, Garcia JI, Smales C, Kelly EE, Marks J,
Malhotra A, Shea SA. Repeated melatonin
supplementation improves sleep in hypertensive patients treated with
beta-blockers: a randomized controlled trial.Sleep
2012; 35(10): 1395-1402. doi:
10.5665/sleep.2122. PMID: 23024438;
PMCID: PMC3443766.
Watanabe H, Martini AG, Brown EA, Liang X, Medrano S, Goto S, Narita
I, Arend LJ, Sequeira-Lopez MLS, Gomez RA. Inhibition
of the renin-angiotensin system causes concentric hypertrophy of renal
arterioles in mice and humans.JCI
Insight 2021; 6(24): e154337. doi:
10.1172/jci.insight.154337. PMID: 34762601;
PMCID: PMC8783690.
Yamal J, Martinez J, Osani MC, Du XL, et al. Mortality
and Morbidity Among Individuals with Hypertension Receiving a
Diuretic, ACE Inhibitor, or Calcium Channel Blocker: A Secondary
Analysis of a Randomized Clinical Trial.JAMA
Netw Open 2023; 6(12): e2344998. doi:
10.1001/jamanetworkopen.2023.44998.
Zhou X, Davenport E, Ouyang J, Hoke ME, et al. Pooled
Data Analysis of the Long-Term Treatment Effects of Tolvaptan in
ADPKD.Kidney Int Rep 2022;
7(5): 1037-1048. doi:
10.1016/j.ekir.2022.02.009. PMID: 35570988;
PMCID: PMC9091612.
Perneger TV, Whelton PK, Klag MJ. Risk
of kidney failure associated with the use of acetaminophen, aspirin,
and nonsteroidal antiinflammatory drugs.N
Engl J Med 1994; 331(25): 1675-1679. doi:
10.1056/NEJM199412223312502. PMID: 7969358.
Loomans-Kropp HA, Pinsky P, Cao Y, Chan AT, Umar A. Association
of Aspirin Use With Mortality Risk Among Older Adult Participants in
the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.JAMA Netw Open 2019; 2(12): e1916729.
doi:
10.1001/jamanetworkopen.2019.16729. Erratum in: JAMA Netw Open
2020; 3(1): e1921081. PMID: 31800071;
PMCID: PMC6902761.
Ross E. The Paleo Thyroid Solution 2nd
Edition. Bradventures LLC; 2020.
Kalish D. The Kalish Method: Healing
the Body, Mapping the Mind. (Please add publication year here).
Brandão R, Santos FW, Zeni G, Rocha JB, Nogueira CW. DMPS
and N-acetylcysteine induced renal toxicity in mice exposed to
mercury.Biometals 2006;
19(4): 389-398. doi:
10.1007/s10534-005-4020-3. PMID: 16841248.
Zalups RK, Gelein RM, Cernichiari E. DMPS
as a rescue agent for the nephropathy induced by mercuric chloride.J Pharmacol Exp Ther 1991; 256(1):
1-10. PMID: 1671092.
Nathan N. Toxic: Heal Your Body from
Mold Toxicity, Lyme Disease, Multiple Chemical Sensitivities, and
Chronic Environmental Illness. Victory Belt; 2018.
Levy TE. Hidden Epidemic: Silent Oral
Infections Cause Most Heart Attacks and Breast Cancers. Medfox
Publishing; 2017.
Appendices: III FAQs
Hattah DKA, Sjahril R, Sriwijaya S. The
Turbidity, pH, Direct Gram as Predictors of Symptomatic Urinary Tract
Infections in Pregnant Women.Nusantara
Medical Science Journal 2022; 7(2): 98-105.
For more information and to purchase a written copy of the book, click here.